Isopropyl Salicylate
- CAS Number: 119-36-8
- Chemical Formula: C10H12O3
- MOQ: 1000KG
- Shelf Life: 2 years
- Forms: Liquid
- Synonyms: Isopropyl ester of salicylic acid, 2-Hydroxybenzoic acid, Isopropyl ester, Salicylic acid isopropyl ester
Product Description
What Is Isopropyl Salicylate?
The salicylic acid ester isopropyl salicylate has anti-inflammatory and analgesic effects. For pain management, especially for ailments like joint and muscle pain, it is frequently utilized in topical formulations such as lotions, ointments, and creams. Its appealing scent also makes it a widely used ingredient in fragrances and cosmetic products. The compound is also found in products like liniments and massage oils.
Preparation Method:
With the aid of a sulfuric acid catalyst, salicylic acid and isopropyl alcohol undergo an esterification reaction to produce isopropyl salicylate. To encourage the creation of ester, the reaction mixture is heated. Afterward, the product is purified by distillation or recrystallization to remove impurities. The end product is a transparent liquid that can be included into a number of cosmetic and pharmaceutical items.
Related Parameters:
| Items | Standards |
| Purity (by GC) | ≥ 98% |
| Refractive Index (at 20°C) | 1.522 – 1.524 |
| Density (at 20°C) | 1.115 – 1.125 g/cm³ |
| Boiling Point | 213 – 215°C |
| Acid Value | ≤ 0.1 mg KOH/g |
| Water Content | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Assay (Isopropyl Salicylate) | ≥ 98% |
Recommended Dosage of Isopropyl Salicylate:
| Applications | Dosage |
| Topical Pain Relief | 5.0%-8.0% |
| Cosmetics & Fragrances | 0.8%-1.0% |
| Massage Oils | 2.0%-4.0% |
| Liniments | 5.0%-8.0% |
| Aromatherapy | 0.1%-0.3% |
Isopropyl Salicylate Has Wide Range of Uses:
1. Topical Pain Relief
Commonly used for pain relief, creams, lotions, and gels are especially effective for alleviating muscle and joint discomfort. It provides anti-inflammatory and analgesic effects.
2. Cosmetics & Fragrances
Added to cosmetics and perfumes for its mild, pleasant fragrance. It’s commonly used in lotions, deodorants, and other personal care products.
3. Massage Oils
It is added to massage oils for its soothing and muscle-relaxing effects, helping to alleviate soreness and tension.
4. Liniments
It is present in liniments used to treat muscle aches and sprains, where it helps alleviate pain and inflammation.
5. AromatherapyTo encourage relaxation and reduce tension, it is added to essential oil mixes and used in diffusers.
User Asked Question:
Q: Can Isopropyl Salicylate relieve muscle pain and arthritis?
A: Isopropyl salicylate’s analgesic and anti-inflammatory qualities make it a popular choice for treating joint and muscular pain. It is found in topical products such as creams, gels, and massage oils, providing effective pain relief for conditions like arthritis, muscle soreness, and sprains. By reducing inflammation and discomfort, it becomes an ideal ingredient for pain relief formulations.
